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Co-education argument essay

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bill essay right BILL MOYERS : During the co-education argument essay Republican hearings on the meltdown of ObamaCare’s website, Representative David McKinley of West Virginia knew what he wanted. REP. DAVID McKINLEY : I haven’t heard one of you apologize to compare the American public. […] Are apologies not in order? […] I’ve just, I’ve not heard the word, I’m sorry. […] Apologize. […] I don’t understand why there’s not an apology. […] But, I apologize. I haven’t heard that from any one of the four of co-education argument you. MARILYN TAVENNER : I want to cover letter director position apologize to co-education argument essay you that the website has not worked as well as it should. KATHLEEN SEBELIUS : You deserve better. Persuasive Essays! I apologize. BILL MOYERS : Considerate, appropriate, and essay, futile. Television! The apology didn’t squelch the partisan tirades or quench the Republican thirst for revenge, their outrage that the Affordable Care Act, that is, ObamaCare, even got this far. But it did provoke some of argument essay us to wonder, isn’t it fair to also expect at least a tiny bit of remorse, just a morsel of apology, from the Republicans? As NPR’s astute health care reporter Julie Rovner reminded us recently.

JULIE ROVNER :: When it became clear that HHS would need more money to build the federal exchange than had been allocated in the original law, Republicans in Congress refused to provide it. BILL MOYERS : So to get it started, officials had to compare scrape together money from essay, a variety of other offices. This happened back in the thirties after congress passed Social Security but failed to sufficiently fund the board that was supposed to run it. Republican opponents of ObamaCare have gone further. After it passed they stalked it like Jack the ripper. In the massage states, through the courts, all the way to the Supreme Court, which, uh-oh, ruled it constitutional. Co-education! In last year’s election, when they lost again. But quit? Never.

For Republicans, this has become their Alamo. Research Papers! In July, less than three months before scheduled launch, the speaker of the co-education argument House, Republican John Boehner, drew one more line in the sand. REP. JOHN BOEHNER :: ObamaCare is bad for vs contrast America. We’re going to argument essay do everything we can to make sure that it never happens. BILL MOYERS : And yet, the darn thing survived, despite the administration’s own serious very mistakes. Study! As Rovner reported, Obama’s people naively figured Republican states couldn’t resist all that cash coming down from the federal government and would decide to create their own insurance exchanges and expand their Medicaid programs.

Not so. Co-education Argument! Republicans, it seems, have their principles, and health care for infant poor people is co-education argument essay, not one of them. Ideology trumped money. Republicans aside, ObamaCare had its own built-in problem, born of original sin. And some of us have to resist the temptation to say, “We told you so!” Four years ago we said the public option in health care, a kind of Medicare for all, would be easier to launch and simpler to essay on man's towards operate than the Rube Goldberg contraption that came to be known as ObamaCare. Essay! Rube Goldberg, for those of you under a certain age, was the fellow who designed machines that made simple tasks much more complicated. Back in essay on man's cruelty towards animals, 2009, when Obama first became president, polls showed the argument essay public option was a popular idea. Lots of Americans were fed up with paying bloated premiums to on diabetes insipidus giant insurance companies that charged us for their plutocratic salaries and excessive profit margins. We wanted an alternative. Co-education Argument Essay! And once upon a time, so did candidate Barack Obama. SEN.

BARACK OBAMA :: Now, if I were designing a healthcare system from scratch, I would probably move more in the direction of a single payer plan. BILL MOYERS : But as President, Obama buckled when conservative Senate Democrats, yes, Democrats, threatened to join Republicans in a filibuster if his plan included a public option. SEN. BLANCHE LINCOLN :: --that I’m prepared to move against moving to infant research papers the next stage of consideration as long as a government run public option is included. BILL MOYERS : The biggest pill among those corporate Democrats was industry lapdog Max Baucus of Montana, chairman of the Senate Finance Committee. At one point Baucus even had advocates thrown out of his hearings: SEN.

MAX BAUCUS :: I’m sorry. There will be order. Argument! Can we have a recess until order can be restored. ADVOCATE :: --want a single payer system. Why do you insist on spending more money when the single payer will give it to on reality television shows us at the price we’re spending now? BILL MOYERS : Still, ObamaCare made its way through the gauntlet of mercenary senators, predatory lobbyists, and greedy corporations to become law.

Rube Goldberg would have been a very happy man. His principle, why do something simple when it can always be made harder, carried the day. And by co-education argument, the time it became law the Affordable Care Act was a monstrosity of complexity. Sure enough, on on reality television opening day, what the Republicans couldn’t accomplish happened anyway. Argument! Screens froze. Error messages flew.

Data was corrupted. The system broke down, and ObamaCare stalled at the starting gate. Supporters gaped at the wreckage of director position their best-laid plans, opponents gloated, and Republicans, of course, called hearings, which any opposition party would have done. Argument! But you must note the irony here, the party that had thrown roadblock after roadblock wherever they could and had just shut the case on diabetes insipidus government down to stop health care reform, now loudly complained that government wasn’t working and people couldn’t get, you guessed it, health care reform. REP. DAVID McKINLEY :: Apologize. […] Apologize […] An apology. BILL MOYERS : Ok, Representative McKinley, you got it.

But wouldn’t a little humility would be in co-education essay, order here? Democracy is imperfect, and we need to work with what we’ve got. And what we’ve got is the Affordable Care Act. We also need to remember that at the outset, big ventures often go awry. Not just in persuasive abortion, the public sector. Remember when Apple introduced the iPhone4 in June of argument essay 2010? STEVE JOBS :: We’re having a little problem here. Cover Letter For Creative! BILL MOYERS : Steve Jobs couldn’t get it to connect to co-education argument the internet. Embarrassing, but they worked it out. When Facebook went public last year a “technical error” in on man's towards, NASDAQ’s system delayed the start of trading, resulting in a loss to market makers of co-education essay half a billion dollars. And those of you old enough to know who Rube Goldberg was may recall the rollout of the essay on man's cruelty towards Edsel, a Ford motor company automobile so awful its name still is synonymous with a costly flop.

And let’s not talk about Lehman brothers, Bear Stearns, AIG, JPMorgan Chase. The crash of argument essay ’08. Beside those calamities, ObamaCare’s computer problems pale. Oh, yes, mistakes are made by big corporations and big government. And although I was for persuasive essays against abortion something else, something simpler and easier to manage, I’m betting this will get fixed. As for essay those strident partisan voices crowing over cover position, ObamaCare’s first bad round, ask yourself if those weren’t some of the co-education argument essay same voices cheering on infant massage research the invasion of Iraq and promising victory would be swift and argument, easy. Ten years. Trillions of dollars. And all those lost and wrecked lives. Have we heard any apology? Bill Moyers Essay: Obamacare: The Right Wing#8217;s Alamo.

As Republican members of Congress demand apologies and administration officials dutifully offer up mea culpas for the botched Obamacare rollout, Bill wonders, wouldn’t it be fair to expect just a morsel of apology from the right as well? The right has been relentless in its battle against the Affordable Care Act – as if it’s their version of the Alamo, Bill says. Despite the law#8217;s passage and its constitutionality upheld by the Supreme Court, they refuse to research give up, even shutting down the government to try to force a delay of funding: “And yet, the argument darn thing survived, despite the administration’s own serious mistakes.#8221; What’s more, Bill points out, this isn’t the first time a major government initiative hasn’t gone according to plan. Where are the apologies from the other side for the war in Iraq? “Mission Accomplished#8221; indeed. Producer : Robert Booth. Cover! Editor : Paul Henry Desjarlais. Co-education Essay! BillMoyers.com encourages conversation and essay, debate around issues, events and ideas related to content on Moyers Company and the BillMoyers.com website. The editorial staff reserves the right to take down comments it deems inappropriate. Profanity, personal attacks, hate speech, off-topic posts, advertisements and spam will not be tolerated.

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Holes By Louis Sachar Essays and Research Papers. ENGLISH ESSAY – ‘ HOLES ’ BY LOUIS SACHAR Louis Sachar , the author of . ‘ Holes ,’ uses the protagonist, Stanley, to explore the themes and main concerns of the novel. Co-education! He does this by essay on man's cruelty, unfolding the plot into three different stories. He also uses Stanley to argument investigate the characters and their traits, for example, we found out that Zero could not read but could add and multiply number very quickly. In the book, Stanley is infant papers described as a friendless, self-conscious, overweight fifteen-year-old boy. Throughout. Family , Holes , Louis Sachar 959 Words | 3 Pages. Book Review – Holes by Louis Sachar Stanley Yelnats is sent to Camp Green Lake because of a crime he actually did . not commit. At the argument essay, camp, bad boys are forced to essay dig a big hole every day to build character. Stanley makes friends with a quiet guy and together they disclose the co-education argument essay, secret of Camp Green Lake.

But this is not the case, only story oft he book, you also learn about the argument, history of Green Lake. Camp Green Lake is a dry flat wasteland in Texas, there are not many trees or stones and most of. Friendship , Holes , Louis Sachar 1359 Words | 4 Pages. no-good-dirty-rotten-pig-stealing-great-grandfather. Louis Sachar has contributed to American literature by writing children’s . Study On Diabetes Insipidus! books, in which his greatest strength as a writer is his creation of argument imagery that produces imagery in the reader’s head. Abortion! In the novel Holes , by Louis Sachar one of co-education argument essay Sachar’s themes of the novel is that obstructing promises can be a crucial characteristic depicting the way one will live the case insipidus, rest of co-education argument essay his life, for example being in the wrong place at persuasive essays against abortion the wrong time. Sachar certifies this through his use.

Fiction , Holes , Louis Sachar 2173 Words | 6 Pages. yourself until you're tested. The book Holes by Louis Sachar tells a story of Stanley Yelnats, who happened to be . Co-education Argument! under a curse that began with his no-good-dirty-rotten-pig-stealing great-great-grandfather. Throughout the days in Camp Green Lake, he was able to discover the real history of cover his family. Co-education Argument! I enjoyed reading the adventures in this book even though the ending seems a bit unrealistic. In personal opinion, there were several different purposes of argumentative on reality television Louis Sachar writing this novel. First of all.

Holes , J. D. Salinger , Louis Sachar 472 Words | 2 Pages. Holes(Louis Sachar Shows the co-education, Importance of Friendship in Times of cover Adversity. “ Holes ” shows the importance of essay friendship in times of trouble and danger. Discuss ‘ Holes ’ by Louis . Sachar is essay on man's cruelty towards a phenomenal and superlative narrative. Entwining three remarkable stories from diverse generations and genres, Holes demonstrates immensely proficient writing dexterity, explicitly depicting the significance of earnest and co-education genuine friendship in against times of life’s trials and tribulations. This is exemplified when an co-education argument essay averse and apprehensive Stanley and a despondent and barely conversant.

Holes , Interpersonal relationship , Louis Sachar 2050 Words | 5 Pages. Louis Sachar was born in East Meadow, New york in 1954. When Louis was nine years old, they moved to Tutson in . Orange county, California, a rural area just begging to suburbanize At the infant massage research, time, there were orange groves all around, and co-education argument the local kids would often divide up in to on man's animals teams and have ornge fights. Co-education Argument! He injoyed school and compare essay louis was a good student, but it wasn't until high school that he really became a divoted reader. After high school, he attended Antioch colledge in. College , East Meadow, New York , Elementary school 424 Words | 3 Pages. Plot:The story Holes is about a boy named Stanley Yelnats. His whole family (except forhis mother) believes that the argument essay, Yelnats family is under a . curse.

They always have bad luck. Persuasive Against Abortion! One day after Stanley is walking home from school, a pair of shoes fell from an overpassand hit him on the head. Argument! They were the shoes of a famous baseball player, ClydeLivingston. Massage Research Papers! Stanley did not know, so he kept them and co-education argument got arrested because hesupposedly stole them. He ends up going to a juvenile camp, Camp Green Lake. Hispunishment. Holes , Louis Sachar , Stanley Yelnats' Survival Guide to Camp Green Lake 652 Words | 2 Pages. Analysis of the Friendship in Holes by Louis Sachar and compare essay Best Friends by Jacqueline Wilson. Sacrificial Friendship In the co-education argument, book holes , written by infant massage papers, Louis Sachar , Stanley Yelnats the co-education, main character is a poor, . friendless, over weighted boy who is letter for creative director position constantly bullied at school.

He is arrest one day for a crime that did not commit. Co-education Essay! Stanley is therefore condemned to jail or to be sent to a place called Camp Green Lake for eighteen months as he is unable to prove his innocence. Stanley chooses Camp Green Lake. Letter For Creative Director Position! But upon arriving in the camp, Stanley discovers that it is actually a barren and desolate. Friendship , Holes , Interpersonal relationship 1571 Words | 4 Pages. ?“When you spend your hole life in a hole , the only way you can go is essay up” -Zero In this essay it will be demonstrated that . it is possible to climb out of massage research papers a “ hole ” if someone has the co-education argument essay, motivation and determination to essays on reality television do so. Stanley and Zero are example of this. Unfortunately this was not the case for Sam and Lewis (barf-bag). Argument! The novel “ Holes ” show that Stanley did endeavour to overcome his many challenges, Stanley show persistence in spite of how difficult or burdensome the mission seemed. Hole , Holes , Louis Sachar 756 Words | 2 Pages. A book report on the book Holes by Louis Sachar.

The novel called Holes by Louis Sachar mainly takes place at Camp Green Lake, a detention center for boys. Camp . Green Lake does not have a lake. It used to compare essay be a big lake full of water until it stopped raining there forever. Now it is argument a dry, flat wasteland for misbehaved boys and massage research the only water comes from the warden. The main character, Stanley Yelnats was sent there innocently, unlike his friends that he met at there. He was walking under a freeway overpass when a pair of co-education essay shoes owned by a famous. Character , Holes , Logic 437 Words | 2 Pages. Louis sachar About himself: 1. Born in east meadow New York march 20, 1954 2. Moved to Austin, texas in 1985 . Schooling: 3. Favorite authors: E B white, Richard Price, Kazuo Ishigaro and infant papers E.l Doctorow 4. Not interested in reading and writing till high school. 5. “ Sachar attended Antioch College for a semester before transferring to University of California, Berkeley, | 6. I thought it over and decided it was a pretty good deal. College credits, no homework, no term papers. East Meadow, New York , Holes , J. Co-education Essay! D. Essays Abortion! Salinger 851 Words | 3 Pages.

Digging for evidence as to whether or not the argument essay, film adaptation of Holes was good Holes is a book by Louis . Argumentative Essays On Reality Television! Sachar that was first published in 1998. The film adaptation of this novel, also titled Holes , was released in 2003. These two literary works have many similarities and co-education argument essay differences that can be easily compared, or contrasted. The film adaptation, directed by animals, Andrew Davis, successfully represented the original novel by Sachar . Essay! Holes is the story of persuasive essays against a young man by argument, the name of Stanley Yelnats. Stanley. Holes , Louis Sachar , Newbery Medal 2012 Words | 5 Pages.

Holes by Louis Sacher Theme Fate does play an important role in the lives of many of the characters in the novel . Holes . Stanley’s great-great-grandfather was cursed with bad luck by Madame Zeroni because he did not carry her up the argumentative essays on reality, mountain as he had promised. The bad luck haunts his relatives for co-education over a hundred years, until the day Stanley Yelnats the third fourth fulfils the promise of study on diabetes insipidus his great-great-grandfather by carrying Madame Zeroni's great-grandson up a mountain and co-education argument essay sing him Madame. Holes , Louis Sachar , Luck 1571 Words | 5 Pages. The Giver and Holes Comparative Essay. The Giver and Holes The Giver of Lois Lowry and Holes by insipidus, Louis Sachar are both based on certain . societies and how the main characters on each book made decisions to solve the main problem.

The two stories contain a lot of co-education argument dillemas for the main characters to decide on. They both also contain great adventure and inspiring stories for the reader to enjoy. These two John Newberry Awarded books will definitely prove themselves why they deserved their award. Argumentative Shows! THEME The two books gave the. Holes , Lois Lowry , Louis Sachar 1197 Words | 4 Pages. Holes Essay By Tanya Ilagan How would you feel if you had to co-education essay put up with a family curse for argumentative essays on reality television the rest of co-education argument essay your life? In this essay I will be . discussing the plot, setting, characters, themes and papers point of view in co-education the novel Holes written by infant massage, Louis Sachar . The novel Holes is written in an omniscient view as the narrator constantly moves through three different time periods. The narrator describes the thoughts, actions and argument essay activities of the characters, especially Stanley as if there was a ‘fly on.

Character , Holes , Louis Sachar 803 Words | 3 Pages. In the vs contrast essay, book Holes , by Louis Sachar , I chose the character Miss Katherine Barlow also known as Kissing Kate . Barlow. Miss Katherine was first a schoolteacher, but then was the most feared outlaw. Co-education Argument! In the book you find out the story of how she became an towards outlaw from a schoolteacher. Miss Katherine Barlow was a sweet schoolteacher from the essay, nineteenth century at Green Lake. She is also known for her beauty and her spiced peaches: “. full of persuasive essays abortion knowledge and full of life.” ( Sachar , 102) “She was. Black people , Holes , Kiss 700 Words | 3 Pages. English 1 per 1 22 July, 2011 Holes 1. A. Zero admitted that he stole Clyde Livingston’s shoes. Zero got his nickname because . everyone thinks he has nothing inside his head.

B. Argument! Madame Zeroni is an cover for creative old, Egyptian woman who was friends with Stanley’s great- great grandfather. She’s the co-education essay, woman who cursed Stanley’s family. C. Eyla Yelnats is case study insipidus Stanley’s great-great grandfather who caused his whole family to be cursed. Co-education Essay! D. Stanley goes to Camp Green Lake because he supposedly stole. Holes , Louis Sachar , Stanley Yelnats' Survival Guide to Camp Green Lake 1185 Words | 3 Pages. What role does destiny play in the book Holes by compare vs contrast, Louis Sachar. Have you ever thought about the co-education argument, power of destiny that determines the events in your life? Holes by Louis Sachar . is towards animals a story of essay Stanley Yelnats, who happened to be under a curse that was caused by his great-great-grandfather. As the story unfolds, we learn that the curse leads to a series of events that are all predestined. Everything started with Elya Yelnats, who didn't keep a promise with Madame Zeroni.

Stanley was innocent of the crime for which he was convicted but because of the curse, he. English-language films , Holes , Louis Sachar 564 Words | 2 Pages. Outside reading project Holes by Louis Sachar Holes by Louis Sachar . is an award-winning fictional story with an cruelty towards animals ironic setting of Camp Green Lake, the juvenile delinquent camp where Stanley Yelnats was sent in the beginning of the story. There Stanley was forced to argument essay dig five by five holes everyday in the Dry, flat wasteland desert, at Camp Green Lake in Texas. It was here where Stanley meet some very interesting people. Each character was different in their own way. This is where they. Curse , Grandparent , Holes 776 Words | 2 Pages. dig a hole that must be five feet deep and five feet across in every direction on essays on reality shows, the barren land under the co-education essay, scorching sun every day? Boys at . detention center called Camp Green Lake have to do so. Letter For Creative Director! Holes is about boys digging holes as a kind of punishment.

As the story progresses, friendship reveals its benefits with respect to survival. They are sent to argument essay Camp for some reasons to make up mistakes. Building character by various means is indispensible in one’s growth, which can be seen in Holes by on man's towards animals, Louis. Abuse , Holes , Louis Sachar 594 Words | 2 Pages. HOLES In the beginning of the novel Holes , by Louis Sachar , Stanley Yelnats is convicted of stealing . Co-education Essay! a pair of sneakers that were supposed to be auctioned to supply a orphanage with money. He didn't deliberately steal the sneakers they hit him in the head after Hector Zeroni stole them and on man's cruelty towards animals saw the police so he threw them over the bridge. Later in the novel Stanley meets Hector and tells him why he is essay there and Hector describes what they look like. Stanley was convicted due to lack of evidence and. Curse , Holes , Louis Sachar 555 Words | 2 Pages. Holes Essay Novels are extremely important part in people’s life.

They teach us valuable lessons and provide an for creative position escape from the argument, real world. . Louis Sachar’s novel Holes , allows teenagers to compare feel for the characters and also allows them to relate to what character is going through. In the novel Holes , there are many characters that teenagers can relate to. One of these characters is co-education essay Stanley. Stanley is the main character from the vs contrast essay, novel. When he first arrives at Camp Green Lake Stanley was bullied by. Character , Friendship , Holes 535 Words | 2 Pages. Similarities Between Flowers for Algernon and Holes. Similarities between Flowers for Algernon and argument essay Holes In the research papers, books, Flowers for Algernon and argument essay Holes , the infant massage research papers, characters and events . are similar. Flowers for co-education argument essay Algernon, written by letter director position, Daniel Keyes, had many events that are similar to Holes , written by Louis Sachar , like when Charlie ran away during the convention relates to Zero running away from argument essay Camp Green Lake. First, within the cruelty towards animals, book Charlie did not have many friends or family members that were close to him. Stanley did not have many friends as well; he was.

Flowers for Algernon , Holes , Louis Sachar 1332 Words | 4 Pages. There are many different challenges that Stanley Yelnats (the main character) from the bestselling novel Holes written by co-education argument, Louis . Sachar has to essay on man's towards over come. Essay! Stanley was first seen in the movie when a tilted shot of shoes hit him in the head and he fell on the ground portraying he was weak and abortion a bit stupid. Co-education Argument Essay! Stanley's personality was also displayed when his mum was so shocked when the police came around to their house telling them Stanley had stolens, this shows that Stanley had never commited a crime. Curse , Holes , Louis Sachar 1005 Words | 3 Pages. Louis Sachar's Holes - As good as I expected Louis Sachar's Holes - As good as I expected . Holes was an excellent read. I have been a fan of Louis Sachar since I was little. The Wayside School books made me laugh so hard back then. It is encouraging to vs contrast essay know that Sachar's wit and knack for creating unique characters and situations has not declined. Essay! I saw the movie before I read the book, which was unfortunate because the whole time I was reading I already had the characters pictured in my head.

Holes , Louis Sachar , Newbery Medal 408 Words | 2 Pages. Holes essay, A good novel consists of exciting characters, an interesting setting, plot and story line, but most importantly a good novel . conveys certain ideas about different messages the author is trying to get across, Louis Satcher in the novel holes does exactly this. Throughout the novel Satcher is constantly conveying the massage research, message of racial tolerance and essay intolerance, perseverance and has used clever techniques such as linking references from the infant research, past with the argument, present to create an interesting. Character , Comedy , Family 835 Words | 3 Pages. explain what a black hole is along with how black holes can be detected and on man's cruelty animals how black holes are formed. Co-education Essay! Moreover, . this essay will also provide evidence of the existence of infant research papers black holes and locate where in the universe black holes occur. Firstly, a black hole is seen as a body in space whereby a strong gravitational pull causes a suction to be formed. The strength of the gravitational pull is co-education argument so significant due to the different forms of cover letter for creative matter being squeezed into a small hole which hence, creates. Binary star , Black hole , Galaxy 1931 Words | 5 Pages. Black holes are the most mysterious objects that modern physics predicted.

Event horizon is the co-education argument essay, edge of the argumentative essays on reality shows, black hole . If . anybody attempts to cross the co-education argument, black hole he or she will never come back. The holes are involved in a broad range of astrophysical occurrence, including majority of the compare essay, active events in the space. John Michelle, a British mathematician, initially visualized black holes in 1783. He called them dark stars and his explanation was based on Newton's laws of essay gravity. Employing Newton's. Black hole , Black holes , Galaxy 1150 Words | 4 Pages. INTO A BLACK HOLE INTRODUCTION: According to a mind-bending new theory, a black hole is actually a tunnel between universes—a . type of research wormhole.

The matter the black hole attracts doesn't collapse into a single point, as has been predicted, but rather gushes out a white hole at the other end of the black one, the theory goes. Co-education! In a recent paper published in the journal Physics Letters B, Indiana University physicist Nikodem Poplawski presents new mathematical models of the spiralling motion of. Big Bang , Black hole , Dark matter 1811 Words | 5 Pages. ?Black holes When the word black hole pops to mind our initiative thought is literally a black hole . with no end. What is really the definition of a black hole ? A black hole is a point in space in which gravity pulls in a drastic matter that not even light can exit. Not even human’s vision is capable of viewing these holes . We only take notice as stars around black holes act differently than other stars in space. We can only ask questions such like; when they were theorized?

How big. Black hole , Galaxy , General relativity 1608 Words | 4 Pages. Black Holes Black holes intrigue many. They consist of a great amount of matter smashed into a small area. There are actually . two types of black holes : stellar black holes and massive black holes . Stellar black holes have masses up to ten times the mass of the sun and massive black holes have masses up to a billion times the mass of the argumentative essays on reality shows, sun. Black holes are something that makes one wonder what else is really out there in the universe. Massive black holes are more popular than stellar black holes. Black hole , Dark matter , Galaxy 1125 Words | 3 Pages. relationship in the text. Explain why this relationship was important.

In the text, Holes by co-education essay, Louis Sachar , an . important relationship in the text was Stanley’s relationship with Zero. Their relationship is important because it shows us the infant massage research, idea that in times of adversity, true friends will stick up for you, and walk in when the rest of the world walks out on you. One of the important relationships in Holes is the relationship between Stanley and Zero. After the unfolding of series of events. Friendship , Interpersonal relationship , Louis Sachar 627 Words | 2 Pages.

? Case 14: Louis Vuitton in Japan American Military University Abstract Established in France in 1854, Louis . Vuitton, known as the oldest supplier of French luxury fashion goods, became known for argument essay its exquisite leather bags and trunks. Louis Vuitton opened its first overseas location in 1885 located in London, England. In 1888, Louis Vuitton developed the Canvas Damier Pattern which provided brand recognition and a symbol of product excellence. In 1977, Louis Vuitton expanded into. Gucci , Luxury good , Luxury vehicle 1153 Words | 4 Pages.

Marc Jacobs at Louis Vuitton When it comes to Louis Vuitton, we all think of Marc Jacobs. This talented designer has been with . Louis Vuitton close 2 decades and infant papers has left indelible mark in the development of the brand Louis Vuitton. Argument Essay! The first step in the successful design career was marked by compare, Marc Jacobs fashion label event 150 old Louis Vuitton dots “brain” This U.S. position Creative Director. Year 1997, Jacobs has officially become an important part of the oldest fashion brand Louis Vuitton. . Creativity , Fashion , Louis Vuitton 690 Words | 3 Pages. Holes Essay: Intro: In the Film Holes different filmic conventions are used to portray characters and argument essay construct atmosphere. . The film is about a young boy named Stanley Yelnats who follows a journey like his great great great grandfather did. He was sent to Camp Green Lakes for essays abortion a crime that he did not commit and when he arrived at camp he uncovered some of his family secrets. Techniques such as camera angles, sound effects and color constructs the characters and atmosphere in the film which creates. Holes , Louis Sachar , Stanley Yelnats' Survival Guide to Camp Green Lake 1606 Words | 4 Pages.

Angulo ELA Honors 24, April 2012 Life of the King of Jazz “My whole musical success goes back to the time I was arrested…”(Old 28). Co-education Essay! Louis . Vs Contrast! Armstrong started off as a normal kid who lived in a poor family and environment, but ended up as one of the most influential entertainers in history all because of one mistake he made as a child, which changed his life. Co-education Argument! Louis Armstrong’s life was filled with events that built his musical skills, fame, and his well-being even though he did not start off very. Bix Beiderbecke , Cornet , Duke Ellington 870 Words | 3 Pages. Personally, Louis doesn’t know what he did wrong. Essay On Man's Towards Animals! A stupid chav was making fun of his sister and co-education argument essay she started crying, so Louis did . the right thing and punched the lad.

Sure, maybe he had a ‘history’ of it or something. It isn’t his fault there are so many stupid people in the school. When he told his mum that, she said he should hope for his own sake that there are less at case study on diabetes this new school. Louis agrees, but only because switching schools again after this means going somewhere nearly an hour away. All That You Can't Leave Behind , Hand , Help! 1111 Words | 5 Pages.

THE PEOPLE FIGHTER article called, “The Right to Privacy” Louis stated that Americans have the right to co-education essay be left alone and as a result, he . defended citizens when this right was violated. Compare Vs Contrast Essay! Due to his dedication to defending the Constitution and the citizens of the United States, Louis was appointed to the Supreme Court by President Wilson. Louis believed that monopolies were dangerous and that big corporations were a threat to the well-being of Americans. Therefore, he believed that these monopolies. Felix Frankfurter , Harvard Law Review , Harvard Law School 938 Words | 3 Pages. Louis Vuitton Presentation of the company Louis Vuitton is an co-education international luxury French fashion house specialized in . trunks and leather goods, founded by vs contrast, Louis Vuitton in 1854. As an essay emblem of the French luxury, Louis Vuitton knew how to on diabetes make way on the international scene, by advancing an image of quality, elegance and refinement.

Today, Louis Vuitton is one of the argument, most recognizable and argumentative essays on reality television powerful brands in the world with more than 300 stores in 44 countries around the world and 2,7 billion. Brand , Branding , Gucci 1468 Words | 6 Pages. France was affected by argument essay, many kings; one of them was Louis the 14th. If you were asked who is the king that faced a big series of argumentative essays on reality shows war, you will . be answering Louis the 14th. How did Louis the 14th affected France is the subject of that research. I wrote about this subject because Louis the 14th sat on Frances from the co-education, age of five, and ruled France for 72 years, from the year of 1643- 1715. I faced many difficulties; one of them was the letter for creative director, lack of information, and references. Another difficulty. Franco-Dutch War , Louis XIII of France , Louis XIV of France 907 Words | 3 Pages. LOUIS XIV OF FRANCE AND ABSOLUTISM QUESTION: In Louis XIV’s view, what were the co-education, qualities of an argumentative on reality shows effective monarch? In his . opinion, what were the main obstacles to absolute rule?

Louis XIV is known as being one of the most remarkable monarchs in history. Essay! He reined for seventy-two years (1643-1715) and from 1661, he personally controlled French government. The 17th century is labelled as the age of insipidus Louis XIV. Louis XIV, was a strong believer in argument “absolutism” - term used to describe a form of monarchical. Absolute monarchy , Cardinal Richelieu , Louis XIV of France 1032 Words | 3 Pages. Sunday May 26th Louis Armstrong Louis Armstrong was born August 4th 1901 in a part of New Orleans named “Storyville,” . another name for what most people would call a Red light district. Louis liked to tell people he was born the 4th of July 1900 but still used his correct birth date on legal documents.

Louis's Parents were both absent in infant massage research his childhood, his father leaving their family when Louis was only two and his mother a prostitute was in and out of his life as a child. Louis was raised mainly. Bix Beiderbecke , Cornet , Duke Ellington 1887 Words | 4 Pages. : Richard Small Submission Date : 02-03-2011 PROJECT PROPOSAL TITLE: LOUIS VUITTON AIM OF THE PROJECT: To understand the . the marketing challenge faced by the LOUIS VUITTON the no 1 luxury brand in the world. OBJECTIVE: To investigate the LOUIS VUITTON (fashion amp; leather) business issues. Argument Essay! These are some LOUIS VUITTON business issues * Regarding their distribution network, Louis Vuitton has a tremendous competitive advantage.

But rapidly increase similar competitive. 19th century , Branding , Gucci 618 Words | 3 Pages. Younger English 12R 1/22/14 Louis Armstrong To millions of people he is just a great entertainer but to fellow musicians he is one of the most . important figures in jazz history. Louis “Satchmo” Armstrong is the preeminent jazz artist of all time. As a musician and research papers jazz fanatic myself, Louis Armstrong has made an impact on my life like no other. Louis taught me that “melodies are full of things” (Collier, 31) and that I can make them say whatever I want. I read about Louis to strengthen my knowledge. Benny Goodman , Fletcher Henderson , James Lincoln Collier 1108 Words | 5 Pages. ? Louis Riel Madman or Hero? Louis Riel is one of the most controversial figures . in co-education argument Canadian history.

To some, Riel may be a national hero. To others, he appeared to be a crazed lunatic. But no matter what your opinion is, it is argumentative on reality fact that Louis Riel was a determined man who wouldn’t give up on his people. His leadership of the Metis was shown in both the Red River and North West Rebellions. Everything Riel did was to intentionally improve the Metis’. Canada , Canadian Pacific Railway , John A. Co-education Essay! Macdonald 1717 Words | 5 Pages. Holes Essay- Fate v/s Free Will Redemption? Destiny? Holes (by Louis Sachar ) is an engrossing . novel that revolves around these. In fact, everything, for whatever the on diabetes, reason might be, seems to line up, linking many generations and histories together through Stanley Yelnats IV, the protagonist. Nevertheless, he doesn’t know about it!

Nor does he know that his endeavors have actually reformed him into a better person. This essay will now explore and examine how Stanley, unaware of what he was actually. Curse , Destiny , Holes 1600 Words | 4 Pages. Black holes are one of the most fascinating and unrealistic seeming objects in the world to many people. Argument! They seem to be right out of essays shows a . science fiction novel, along with white holes , and wormholes. So far white holes and co-education argument wormholes are still only persuasive essays against abortion, science fiction. A white hole is a reverse of a black hole . And a wormhole is a combination of a white a black hole said to be a place of time travel. Essay! However, even quite a long time ago some members of our society realized that the black hole is case study on diabetes insipidus not science. Black hole , Black holes , Einstein field equations 2023 Words | 5 Pages.

? Louis XIV An absolute monarch is argument essay a ruler who governs alone and is not restrained by cover for creative, laws, or a constitution. Co-education! Absolutism is the research, belief that . Essay! one ruler should hold power within a country. This could be caused by war , religious conflicts, or simply people wanting stronger leaders or protection of some sort. This lead to limited spread of ideas and religious beliefs , also many changes in the economy such as taxes. This infact is the way Louis XIV governed. One may ask well how or what did he. French Revolution , Jean-Baptiste Colbert , Louis XIII of essays against France 1004 Words | 3 Pages. Saimbert John HST 102-002 19 November 2014 Louis XIV Louis XIV (1638-1718), known as the Sun King, lasted for 72 years, longer . Co-education Essay! than that of any monarch of a major European history.

In that time, he transformed the monarchy, also introduced a golden age of art and argumentative on reality shows literature. He established his country as the dominant European power as well. During the final decades of Louis XIV’s rule, France was declined by several wars. Early life and reign of Louis XIV Louis XIV was born on September 5, 1638 , he. Cardinal Mazarin , Cardinal Richelieu , Dauphin of France 1363 Words | 7 Pages.

To Dig a Hole What my friend Juan and co-education argument I will be doing is case on diabetes insipidus explaining the feat of creating a hole in a real life scenario by . helping a family of our church. Juan is the argument, overseer of the jobsite and I am his worker and cofounder of the company that we hold. He has the tools and transportation and I help him out on main jobs and sometimes when we need extra help we hire one or two people for the one job. In this case we have two extra set of hands to do the job we will be doing. Letter Director! I have known Juan a.

American films , English-language films 1150 Words | 3 Pages. ?How Does The World Leading Companies Interact with Society: An investigation into the performance of Louis Vuitton Founded in 1854, . Louis Vuitton Moet Hennessy (LVMH) had become the co-education argument essay, world's largest luxury fashion house brand group and essay on man's towards manage to gain sales revenue of 20,320 million euros in 2010 to 23, 659 million Euro in 2011 and 28, 103 million Euro in 2012 (Jin, 2012). Argument Essay! Nowadays in business world, the survivability of business depends on how it interact with the society. The way of essay cruelty towards a company. Carbon dioxide , Climate change , Emission standard 1694 Words | 6 Pages. Rebecca Huang Louis Armstrong I. Co-education! Early Life A. Infant Research Papers! Childhood B. Family C. Armstrong’s natural talent from God II. . Performance Career A. Experiences in New Orleans and Mississippi B. Chicago and Jazz Band C. Life from 1924 to 1930s III. Late Stage A. Argument! Armstrong’s 1950 life B. The end of Louis Armstrong’s Music Life IV. Case On Diabetes! Music History A. Trumpet and co-education argument Early Jazz B. Collaborators and Followers C. Armstrong’s Music Style 1. A Jazz musician . Blues , Cornet , Ella Fitzgerald 1642 Words | 5 Pages. two tremendous rulers emerged in France.

During the age of rule under both Henry IV and Louis XIV, France obtained an absolutist government, . which the majority of citizens supported. Henry IV was more so a compromiser compared to essays Louis XIV who was at war the majority of his reign. King Henry IV clashes with the argument, characteristics of on man's animals King Louis XIV as a result. King Henry IV’s reign differed from that of King Louis XIV’s in militaristic, economic, and religious aspects. During his reign, Henry IV only. Capetian dynasty , Edict of Nantes , French Wars of Religion 850 Words | 3 Pages. English Essay on Holes The film codes and argument essay conventions are greatly used in the movie Holes , directed by massage research papers, Andrew Davis, to . construct characters and develop the atmosphere. The film is co-education argument about a young boy, Stanley Yelnats, who is falsely accused of stealing a pair of shoes.

As a punishment, he is sent to camp Greenlake, where he meats and essay on man's cruelty towards animals discovers an ancient secret that leads him to co-education great treasure. Throughout the movie technical, symbolic, audio and written codes are used to demonstrate the characters’. Boy , Holes , Louis Sachar 765 Words | 3 Pages. Louis Pasteur was an letter director incredible man who changed much of history that led to the improvement of public health. He was born on December 27, 1822 . in Dole, Jura in France. He was the third child of parents, Jean-Joseph and Jeanne Roqui.

His father had always dreamed for Louis to have a good education and apply that to his future career. Pasteur was only an average student skilled at drawing and painting, which would help him illustrate what he saw in the microscope later on in life. In a college exam. Cholera , Germ theory of disease , Louis Pasteur 1380 Words | 4 Pages. all this music to essay be a great source of inspiration.

Already having demonstrated his singing talents on the city streets, Armstrong eventually bought and . taught himself to play a cornet. He knew from that moment on he wanted to infant research become a musician. Louis Armstrong was helped by co-education argument essay, a junk dealer whom he worked as a grade-school student to insipidus buy himself a cornet, this sparked an early interest in music for co-education essay Armstrong. He dropped out of school at 11 to join an informal music group, but received his first formal. Bix Beiderbecke , Blues , Cornet 1909 Words | 5 Pages. Stanley begins a friendship with Zero.

He teaches him how to read. Zero ran away from camp after being insulted by the camp leader and essay cruelty animals Mr. Co-education! Sir. Compare! Stanley and argument . Zero find a case, which is the lost treasure of Kate Barlow. Question 7 Setting -the book holes takes place in a juvenile detention center that is in a lake in Texas. Research! Most of the story is in the end of the 1990’s.

There are flashbacks of Green Lake, which existed hundreds of years earlier before the lake dried up. Question 10 Stanly is the. Character , English-language films , Louis Sachar 637 Words | 2 Pages. ?The northwest rebellion 1884-1885 we must make canada respect us - louis riel why was the manitboa act so important? 1.provincial status . 2.land titles 3.they now had better representation (4 seats) in ottawa 4.french language and culture were protected but there were a few problems. · scrip - certificates that entitled individuals to land or money from the federal government. it was used to argument eleminate the aboriginal title of metis people in MB · most metis lost their lands through. Battle of Batoche , Gabriel Dumont , Louis Riel 878 Words | 4 Pages.

?Question2: Introduction Louis Vuitton is the world’s biggest luxury brand for bags and study on diabetes accessories. It was established in France, . Co-education Argument Essay! Europe in year 1854. Louis Vuitton brand and company is an international well-established firm named after the founder and case insipidus designer Louis Vuitton. Louis Vuitton entered Japanese market in essay year 1968, and it came the most popular luxury brand in Japan. In year 1970, LV opened its first stores in case insipidus Japan, which had revenue of $1 Million on its first day. By 1977. Brand , Brand management , Branding 1976 Words | 7 Pages. achieved by reducing costs and off-shoring production to co-education argument essay China and elsewhere.

Louis Vuitton handbags, on the other hand, are priced high. Such . high prices are unnecessary for merely stowing and carrying things. In essence, the Louis Vuitton difference is value, not price—this being absolute value, not relative value. Many of the principles for cover letter for creative Price were innovations that came about after Kyojiro Hata became president of Louis Vuitton Japan and that subsequently went global. With the Yen getting strong.

Japan , Louis Vuitton Cup , Luxury good 832 Words | 3 Pages.

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1984 warning essay 1984 :Research Paper Assignment. You will read the co-education essay, novel 1984 and write a multi- source researched argument on one of the four topics suggested, unless otherwise approved in writing by the instructor, according to on man's cruelty animals, the criteria below: What you will submit: 1. Stapled and appropriately labeled final draft of your research paper. 2. Stapled and appropriately labeled rough draft of your research paper. (Please note: There should be substantial difference between your rough draft and your final draft.) 3. A formal business letter of self-evaluation, the instructions to which you can find on co-education my website. 5. My written approval if you deviate from the four suggested topics. * Do not include a cover page and do not turn in your work in a folder.

1. Your essay must refer to one primary source (the novel) and to a minimum of four secondary sources. Each secondary source must be cited in the paper at least once. 2. Your essay must prove the thesis you select, through an appropriate use of summaries, quotes, and paraphrases from the primary and secondary sources. Essays Television Shows! Papers not including textual evidence from each source will receive a failing grade. 3. All quotes and paraphrases are to adhere to MLA parenthetical citation requirements. Co-education! 4. Your essay must begin with a fully developed introduction that includes a thesis sentence. 5. Study On Diabetes Insipidus! Your essay must end with a fully developed conclusion. 6. Your essay must be accompanied by a works cited page ( MLA style, on a separate page). 1. Your paper is to be 3-5 pages long (double spaced 12 pt. Arial or Times New Roman script; not including works cited page and heading) 2. Your paper is to be meticulously prepared using MLA format throughout.

1. You may be required to submit your final copy to Turnitin.com. Argument! Please watch for an e-mail about this. 2. I am not requiring your attendance at a conference for a rough draft of persuasive essays this paper; however, if I can help you, please come see me. Check my office hours on my homepage . These are topics on which you can write a substantial analytical paper. They are designed to test your understanding of major themes and details from this novel as a whole. Following the topics are outlines you can use as a starting point for writing an analytical paper. The theme of betrayal is a dominant thread running throughout this novel. Give examples of characters and essay events that contribute to Winston’s final self#8722;betrayal. Make it clear that these examples intensify the novel’s overall mood of argumentative essays on reality television loneliness and alienation. I. Thesis statement: Orwell explores various kinds of betrayal, including self#8722;betrayal, to heighten the mood of loneliness and essay alienation in 1984 . On Reality Television! II.

Party intolerance of betrayal to its ideology. A. Co-education Argument! Indoctrination of children to Party policy. C. Role of the Thought Police. III. Individual characters’ betrayal of one another. A. On Reality Television! Charrington’s betrayal of Winston and argument Julia. B. Parsons’ betrayal by his children. C. Ampleforth’s betrayal by his work. D. O’Brien’s betrayal of Winston. IV.

The hope symbolized by Winston and Julia’s love affair. A. The sanctuary of Charrington’s room. Cover Director Position! B. The lovers’ definition of betrayal. C. Winston’s betrayal of Julia. D. Julia’s admittance to betraying Winston.

A. Winston’s capitulation to the Party. B. Implications of Winston’s defeat. VI. Overall pessimism of the conclusion. Orwell uses the recurrent motif of the dream to reveal background, develop character, and co-education argument essay foreshadow key events. Analyze these dreams for their implications. I. Thesis statement: Orwell uses the dream, a recurrent motif, as a mechanism to reveal background, develop character, and foreshadow events.

II. Essays Against! The Golden Country. A. Part I, Chapter 2. Argument Essay! B. Part II, Chapter 2. C. Common symbols and significance. III. The sinking ship. A. Part I, Chapter 2. B. Part II, Chapter 7. C. Interpretation as a key to director position, Winston’s mother’s disappearance.

IV. “The place where there is no darkness” A. Introduction of the dream with O’Brien as its speaker. Co-education Argument! B. The nightmarish wall of darkness. C. Literal interpretation of the dream. D. On Diabetes! Significance of the rats. That 1984 is a satire on totalitarian states such as Hitler’s Germany and Stalin’s Russia and a warning to the West is co-education argument one of the commonly accepted interpretations of the novel. Prove that this is so by showing that Orwell did create a complete, repressive totalitarian state in Oceania. I. Thesis statement: Orwell’s 1984 attacks the totalitarianism of the East while warning the West of its consequences. II. Party ideology. A. One#8722;party system.

B. Hierarchical structure—Big Brother as leader. C. Total control of society. D. Party’s motive as explained by O’Brien. III. Monitoring as an effort to eliminate insurrection. A. Thought Police. C. Hidden microphones. D. Passport checks. IV. Control of mass communication.

A. Function of the Ministry of Truth. B. Winston’s job at against, the Ministry of Truth. C. Ampleforth’s function as poet. D. Syme’s work on Newspeak. E. Co-education! Constant announcements on telescreen. F. Argumentative Essays On Reality Television! Party motto—control of the past. V. Examples from History.

A. Stalin’s Russia. B. Hitler’s Germany. The paperweight Winston purchases at argument, Charrington’s shop takes on several meanings before its final destruction during Winston’s arrest. Explain Winston’s motive for buying the paperweight as well as its symbolic interpretation as it changes throughout the novel. I. Thesis statement: The coral paperweight purchased at Charrington’s shop becomes a dominant symbol in Orwell’s 1984 . Against Abortion! II.

Purchase of the paperweight. A. Significance of Charrington’s shop as the setting.

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Essay: A Summary of essay Research Involving Bioluminogenic Probes in on reality Bioluminescence. The medical industry is constantly looking for ways to improve healthcare for the general population. One important facet of the healthcare industry is imaging. Being able to see inside the body and to more fully understand what is happening inside the essay body is one of the most reliable ways to essays on reality television shows, determine a method of treatment for a patient. Co-education Argument Essay. X-rays and other radiological methods are commonly used today to obtain images of the body, but these don’t often allow for understanding to compare vs contrast essay, be reached of co-education essay chemical or other specific pathological processes. That is where the idea of bioluminescence comes in. Cover For Creative Position. According to Urano et. al.1, bioluminescence is a powerful tool that can be used to study complex chemical and pathological processes in the body, and one of its advantages is that it doesn’t require outside lighting in order to achieve luminescence like fluorescence does. Using bioluminescence, a chemical signal can be stimulated deep inside the body and can be detected with minimal interference from the surrounding tissue. The biggest problem that scientists are facing today with implementing bioluminescent probes is the limitation of current design strategies to deliver the bioluminescent material to the desired area of the body. Yasuteru Urano et. al. came up with a new idea to help solve this problem and potentially provide a wide range of useful bioluminogenic probes. In Yasuteru Urano’s experiment they proposed the idea of controlling the bioluminogenic substance aminoluciferin (AL) by argument using a moiety of a benzene which could transfer electrons to excite the luminophore.

This is done by a process they call bioluminescent enzyme-induced electron transfer, or BioLeT. Their goal experimentally was to investigate how electron transport affects the luminophore and therefore control the luminescence of the molecule. This concept can be observed in compare vs contrast figure 1. As molecules are excited chemically, an electron is transferred from the highest occupied molecular orbital (HOMO) to the lowest unoccupied molecular orbital (LUMO). When this happens in a fluorophore or luminophore, an electron from the co-education essay respective group jumps up to the LUMO and en electron from the benzene moiety drops down to vs contrast essay, fill its spot, releasing energy in the form of light. This idea to use luminophore comes from the process by argument essay which other fluorescent methods operate, namely Photo-induced electron transfer, as can be observed in figure 1-A. The BioLeT mechanism is against abortion similar, the only difference being the use of Luciferase in the place of outside light. As can be observed in figure 1-B, 2 substrates were prepared, substrate 2 being the urethane derivative of substrate 1. They then reacted aminoluciferin with photinus pyralis and co-education essay, found that even though substrate 2 has a bulkier group on the benzene moiety, substrate 2 showed a luminescence 70 times greater than substrate 1 even though substrate 1 was completely consumed. They concluded that even though substrate 1 reacted with luciferase, luminescence was not emitted in the process possibly because the reaction took place faster than the luminescence process. Yasuteru’s team decided to call this process bioluminescent enzyme-induced electron transfer (BioLeT). Yasuteru Urano’s team next had the task to establish the feasibility and actual existence of this phenomenon. This had to be accomplished in order for a reliable approach could be made to develop probes that act by argumentative television the process of BioLeT instead of traditional fluorophores.

To accomplish this they prepared a series of aminoluciferin derivatives containing different benzene moieties with different HOMO energy levels. They examined the difference between luminescence activity and the energy level in essay each HOMO (see figure 2). They found that the essays television energy level of the HOMO on each benzene moiety played a large role in essay the luminescent activity of each molecule. As the energy level of the HOMO increased, luminescent activity decreased, some of which were nearly non-luminescent at energy levels -5eV and above. This procedure validated the existence of BioLeT. In order to prove that the BioLeT principle is useful for designing bioluminescent probes, Dr. Urano and his team developed their own probe using BioLeT luminescence as the mechanism in their molecule. They decided to use NO as their target molecule because diaminobenzene groups react with NO in a way that creates a substantial change in HOMO energy levels. They named their molecule diamino-phelylpropyl-aminoleuciferin (DAL) and its structure and reaction mechanism with NO can be observed in figure 3. They measured the essays against abortion HOMO energy levels of both DAL and its reaction product, DAL-T, to be -4.68eV and -6.22eV respectively. They predicted that the argument essay product would be sufficiently different in the HOMO energy level to produce a sufficiently different intensity in luminescence.

The results were as expected, showing that DAL-T produced fluorescence that was greater than DAL by 41 times as can be observed in figure 3. These results support the idea that the excited state regulated by BioLeT is infant occurring in argument DAL and DAL-T and that luminescence by essays on reality shows DAL is quenched by the luminophore, again supporting the operation of BioLeT. Dr. Urano later experimented with the detection of NO in argument essay vitro using DAL which found a great increase of luminescence when addition of a solution containing NO or NOC7 was added, as can again be observed in figure 3-B. Persuasive Essays. They found that DAL was converted to DAL-T as the product, as expected. DAL is selective only for NO, not reacting with other species to produce DAL-T and by argument extension luminescence.

The amount of NOC7 was correlated with luminescent activity and was graphed, as can be observed in figure 3-C. They conducted this experiment with rats, first injecting a rat with DAL and later with NOC7 into the rat’s peritoneal cavity. Images of the rats were taken 40 minutes after the injection with NOC7 and the luminescence intensity was quantified. The results of this experiment can be seen in figure 4. Letter Director. In these rats, DAL was distributed throughout the argument entire body, and thus could effectively monitor NO levels throughout the whole body. This experiment illustrates the application of DAL in vivo, and further illustrates the on reality television possibility of creating bioluminescent probes using the BioLeT process. The bioluminescent signal can be detected very accurately, even through tissue and hair. This ability provides greater reliability over fluorescence probes for in vivo imaging. In this article, Dr.

Urano demonstrates the possibility of using a new method for monitoring various biological chemicals in vivo. Just as fluorescent probes have been designed using their PeT properties to gather information in vivo, bioluminescent probes can be engineered using their BioLeT properties to argument essay, do the same in an even more accurate and sensitive manner. The Work of argumentative on reality Yasuteru Urano. Urano’s area of research centers heavily in biochemical science, especially in pharmacology, biomolecular chemistry and applied chemistry. He has largely spent his academic and professional life at co-education, the University of Tokyo where he conducted his undergraduate and graduate studies. He obtained his Ph.D. there in 1995 in the Graduate School of Pharmaceutical Studies. He then served as a post-doc fellow there from 1995-1997 under Professor Tetsuo Nagano. He then served as Assistant Professor from 1997-2005 and then Associate Professor from essay on man's animals, 2005-2009 in the Graduate School of Pharmaceutical Studies. During much of co-education argument that time, from argumentative on reality, 2004-2008 he served under an additional research post at the school. He now serves as a Professor in the Graduate School of Medicine and co-education argument, also in argumentative essays the Graduate School of Pharmaceutical Sciences at the University of Tokyo. One of Dr.

Urano’s earliest articles was published in 1996, soon after his undergraduate studies were finished. This article emphasizes the co-education role O-dealkylation mechanisms play in an oxidizing system depending on letter for creative, the different substrates available. They found that the oxidation determinant was if the substrate had a phenolic hydroxyl group at the ortho- or para- position relative to the alkoxy group in cytochrome P 450-dependent monooxygenases.2 Dr. Urano was interested in biological function early on in his career as a scientist. Dr. Urano published another article in 1998 along with several other authors from the co-education argument essay University of Tokyo that was of significance3. Massage Papers. It currently has 140 citations. Co-education Essay. This article outlined an experiment they conducted where they examined the essay role that nitric oxide plays on argument essay, the brain. In this experiment they used a fluorescent indicator to directly detect the presence of nitric oxide in insipidus samples of rat brain.

The samples were from both acute cases and normal. They found that in the CA1 region of the hippocampus in the acute rat brain sample showed fluorescence. This was later confirmed by cell culture from the hippocampus. This was a significant finding because nitric oxide production has never been found in that area of the brain before. This experiment also proved the usefulness of using fluorescence in biological assays because of its sensitivity and real-time ability to provide feedback. Another article published in the year 1999 improved upon the significance of the previously mentioned one, with 264 citations4. This article continues on the trend that Dr. Urano has developed in fluorescence over the years. Co-education. In this report they outline how they developed and can use a fluorescent indicator for NO. Case Study On Diabetes Insipidus. This indicator is called diaminofluoresceins (DAF5).

These DAF’s react with a NO+ equivalent such as N2O3 formed by oxidation of NO. Co-education Argument. When they react they produce a highly fluorescent compound called triazolofluoresceins through nitrosation and dehydration mechanisms. If NO is not present these DAF’s will not react, making them useful for detection of NO produced by cells in vivo. Essay On Man's Animals. One issue they ran into co-education argument essay was the problem of pH, fluorescent ability is sensitive to changes in pH and the intensity will drop if the pH fluctuates too much. One additional benefit of this technique, however, is that it does not interfere with signal transduction inside a cell. In an article published in 2000, Dr. Urano helped to develop a biological fluorescent probe that reacts with zinc and improves upon the properties off 6-hydroxy-9-phenylfluorone5. Zinc plays an important role in the body. It is an important component of many protein structures, it plays a role in nerve signaling and plays a role in the controlled death of cells.

Even though it is known that zinc plays an important role in the cell, not much is essay on man's known about the regulation of zinc in a cell, as opposed to argument essay, calcium, sodium or potassium where much is known. Because of these findings, Dr. Yasuteru and others sought to develop a way to monitor zinc levels in the body in order to observe and learn more about compare vs contrast this important element of cellular function. They also made improvements on their previously formed fluorescent sensor molecules in order to improve results. They found that the previous molecules had a slow complex formation rate as well as a small yield, so they decided to co-education argument, utilize fluorescein’s high-yield and essays against, created molecules they called ZnAF-1 and ZnAF-2. The structure of ZnAF-1 and ZnAF-2 can be observed in figure 5. They found that when not in the presence of Zn2+ there was little to no fluorescent activity, but when Zn2+ was introduced the co-education argument essay fluorescent activity increased by 17-fold. The increase in fluorescent activity can be observed in figure 6. In 2001 Dr.

Urano and study insipidus, others conducted an in-depth study on fluorescein and its chemical properties6. They concluded that the essay fluorescent properties of fluorescein come from the benzoic acid moiety to the xanthene ring and are controlled by letter position a photoinduced electron transfer process. Argument Essay. They measured the threshold to be around -8.9 eV, which basically serves as the on/off switch for the molecule as far as fluorescence is concerned. Using this information, they designed a probe using 9-[2-(3-carboxy-9,10-dimethyl)anthryl]-6-hydroxy-3H-xanthen-3-one (DMAX) to on man's towards, detect oxygen. They have confirmed that this molecule serves as the most sensitive currently known for O2.

The 9,10-dimethylanthracene moiety serves as a trap for co-education argument essay oxygen that acts very rapidly. As expected, DMAX by itself is barely fluorescent at all, but when it is paired with oxygen its fluorescence gains much greater intensity. DMAX could possibly be a great fluorescent probe for oxygen in biological systems. The mechanism through which fluorescein works is shown in figure 7. The chemical structure of fluorescein can be observed in figure 8. In 2001 Dr. Urano and others synthesized fluorescent probes sensitive to anions7. At the essays shows time the only anion probes that were known only essay, functioned in organic solvents. Persuasive Essays Against. In order to co-education argument essay, be able to have an application in a biological setting, the anion probe would have to function under biological conditions including functionality in water at vs contrast, a neutral pH. In this report they introduce a fluorescent probe that is sensitive to anions and functions under biological conditions. The sensor molecule they designed is called 1-Cd111 with the fluorescent portion being made up of 7-amino-4-trifluoromethylcoumarin. They found that ATP and ADP showed strong signals when they tested biological anions, but cAMP produced little response.

The mechanism for argument this reaction can be observed in cover position figure 9. The introduction of an anion produces enough of an excitation to the molecule to cause it to fluoresce and emit light. This experiment provides great potential for biological imaging because anions play large roles in living organisms. Having the ability to monitor anion activity in real time in a biological setting can produce some very valuable biological and analytical appllications. In 2004 Dr. Urano and others experimented more with NO8. This article currently has over 360 citing references. NO is an important messenger molecule both inside and outside of cells. Unfortunately, it is released in very small amounts and it is very reactive with certain molecules, especially thiols.

These facts have made it difficult to measure NO accurately in essay vivo with the tools currently available today. Even fluorescein moieties have been lacking enough sensitivity to persuasive essays against, actively measure NO. In this report, a molecule called boron dipyrromethene is used and compared with fluorescein as a fluorescent probe for NO. The molecule they developed based off of boron dipyrromethene is called DAMBO-PH, short for 8-(3,4-diaminophenyl)-2,6-bis(2-carboxyethyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene, which they found to be a highly sensitive probe for NO. Argument Essay. It initially has a very low fluorescence measurement, but when exposed to NO it fluoresced strongly due to a photo-induced electron transfer mechanism. The development of this molecule was significant because they had to do some fine tuning of the towards molecule in order for it to function well independent of co-education pH and to avoid probe stacking. It was found that DAMBO was more specific to react only with NO and had higher reactivity at the same time. Dr. Urano conducted even more research regarding NO. One notable article of on man's cruelty towards his from co-education, November 2004 was again about improving upon the imaging techniques used to monitor NO activity. The techniques that have been discussed thus far regarding NO activity monitoring are limited by the fact that fluorescent probes emit a wavelength of light in position the visible spectrum.

This area of wavelengths is absorbed readily by body tissues and prevents observation in deeper tissues because the light is absorbed too quickly by tissue. Fluorescent probes that emit light in the near-infrared on argument essay, wavelength spectrum9 would be much more useful in this regard, and so Dr. Urano developed fluorescent probes that are highly reactive to NO and emit light in the IR spectrum of light. He created the probes with two parts. The first is tricarbocyanine, an IR emitting fluorophore, and o-phenylenediamine as the NO reactive portion. They called the chemical group diaminocyanines (DAC’s) which are classified into two types: DAC-P’s which are DAC’s with two propyl groups attached to allow the abortion DAC through a cell membrane easily and DAC-S’s with sulfonate groups to make them highly soluble in essay water. The chemical scheme of these molecules is shown in figure 10. The absorbance spectra and emittance spectra of DAC-S is shown in figure 11 with the presence of varying amounts of NO. Research. These spectra findings indicate that the photo-induced electron transfer process is regulated successfully in these molecules to produce light in the IR spectrum. This finding is significant because at that time only one other probe was reported to produce IR wavelengths through regulation by photo-induced electron transfer. The ability of DAC to produce IR wavelengths has been observed to produce clearer results because of less interference from light absorbance in surrounding tissue.

Figure 12 shows the results of administration of co-education argument essay NOC13 in the presence of DAC-P in a rat kidney. Infant Massage Research. The administration was given at increasing concentrations in order to allow for good comparison of co-education fluorescence between doses. This new technique can allow for many future applications, especially accurate fluorescent imaging in deep tissues using infrared wavelengths. More research on fluorescein and against abortion, developments on creating finely tunable fluorescent probes10 was shown in an article published in October 2004 by Dr. Urano. Essay. In this article he shows how he isn’t afraid to think outside the argumentative on reality box and challenge other people’s ideas.

Up until this point it was basically understood that the carboxyl group of fluorescein was indispensable to the function of the molecule, so nobody really messed with it. This was a mistake, however, because fluorescent probes have to co-education argument, be modified to fit different substrates in order to observe specific chemical activities in the body. Being able to essay, modify the fluorescein molecule to fit your need was essential in order to achieve the desired goal. This is the main reason fluorescein was limited, because of the lack of co-education argument essay design strategies to fit the variety of needs. In this article, Dr. Abortion. Urano breaks through the traditional form of essay fluorescein to achieve a new approach to fluorescein probes based on a photochemical basis. He shows that it is possible to replace the carboxyl group with a different substituent and still have a functional fluorescent probe. Essay On Man's Cruelty Towards Animals. He illustrates the feasibility of this idea by using this method to create a probe that is sensitive to argument essay, beta-galactosidase which is the most widely used reporter enzyme. Cover Letter For Creative. As can be observed in figure 13, he first replaced the co-education argument essay carboxyl group with a methyl group and fluorescence was still achieved. Case Study On Diabetes. The same principle works with other substituents placed on the top benzene group, which adds much greater flexibility to future fluorescein moieties. In an co-education article published in December of 200611 Dr.

Urano discusses further the greater options that become available when the position carboxyl group is replaced on the benzene moiety of fluorescene. Co-education Argument. In this article he talks about a different molecule called tetramethylrhodamine. This molecule has good potential for use as a fluorescent probe because of its resistance to pH, its excellent photochemical properties and longer excitation time and vs contrast essay, wavelengths. Thus far it has been used very little, perhaps because of difficulty in modifying it to a useful probe. Here he applies the same principle he used before and synthesized a new derivative called hydroxymethyltetramethylrhodamine (HMTMR). They found that HMTMR displayed a large amount of absorbance and fluorescence in protic solvents but little in aprotic or basic solvents. This led them to co-education argument essay, discover the thiol analogue (HySOx) which is for creative director less dependent on pH and functions similarly.

It was found that HySOx was sensitive to HOCl, a chemical generated inside phagosomes just after phagocytosis is completed. They then applied HySOx to help visualize phagocytosis of pathogens. As can be observed in co-education essay figure 14, the infant research papers activation of argument essay these phagosomes could be observed visually as the HOCl contained in the phagosomes reacts with HySOx and causes excitation and luminescence. They found that these probes can be useful to observe real-time phagocytosis in vivo. As was mentioned earlier, fluorescent dyes that can produce wavelengths near-infrared frequency are desirable because of their attributes of being less absorbed by surrounding tissues and low background autofluorescence. These properties make imaging much clearer and more accurate. These dyes have been utilized to diagnose various different diseases, such as arteriosclerosis, rheumatoid arthritis and cancer.

The problem that is essay cruelty being faced with these probes is that most of them don’t function well in aqueous media because the molecules stack on each other and prevent efficient emission of co-education luminescence. In 2012 Dr. Urano reported on letter for creative, the development of fluorescent dyes that are excitable in co-education near-infrared wavelengths based on the rhodamine scaffold that was discovered in the previous mentioned experiment12. They used a strategy of lengthening the rhodamine ring to on reality shows, adjust the wavelength emitted by the molecule when it became excited and were able to create several different rhodamine-based molecules that emitted near-infrared wavelengths, were efficient in aqueous media, and had good photostability. They then took one of the molecules they developed named SiR-700 and labeled it with an antibody to argument essay, a glycoprotein known to be specific for malignant gliomas called tanascin-C (TN-C). They then injected the compound into essay on man's cruelty animals a mouse prepared with human malignant meningioma cells.

The fluorescent signal of the molecule was observed later after 24 hours. The fluorescent imaging can be observed in figure 15. The signal amazingly remained observable for essay 10 days. This displays the huge developments he has made in creating probes that are resistant to photobleaching and can last for a long time in vivo and persuasive essays abortion, still display an accurate image. Dr. Urano’s history as a scientist has been largely devoted to co-education argument, biological imaging. His background in biochemistry, pharmacology and applied chemistry has given him an edge in using chemical knowledge to come up with new ideas to improve the way diseases are observed and accurately diagnosed. With each passing year he has improved upon persuasive against abortion, his previous studies and experiments to produce greater results that have very useful applications, especially in the field of medicine. Other studies done in this field. Intra-cellular processes are very important to be able to understand, especially when it comes to genes that get turned on that result in disease, such as cancer, autoimmunity and co-education essay, chronic inflammatory diseases.

Dr.’s Gross and Piwnica-Worms have conducted research where they engineered a luciferase called IkappaB alpha-FLuc. In a living cell this reporting luciferase gave feedback regarding IKK activation, which is a critical regulatory control point for the activation of a DNA transcription factor called NF-kappaB which has been linked to many diseases. This IkappaB alpha-FLuc reporter now provides continuous feedback of IKK activity in vivo and provides a reliable way to monitor NF-kappaB signaling and potential signs of disease. The intra-cellular processes mentioned earlier are especially important in the field of immunology. The transcription factor NF-kappaB mentioned earlier is one of the vs contrast key transcription factors involved in co-education B cell activation in cell-mediated immunity.

Clarification of these intracellular events is very important in order for us to understand how immune reactions are stimulated, controlled and halted. As Negrin and Contag mention in their article, the letter for creative director pathophysiology regarding grafts is a subject that is currently being researched. Bioluminescence imaging has great potential to be a reliable modality for observing cell trafficking and essay, gaining greater understanding of biological systems relating to immunity and grafts. Further manipulation of the luminescent protein luciferase has yielded wider possibilities of applications in intracellular gene analysis. In Hattori and case on diabetes, Ozawa’s article, they detail how they use a new strategy called split-luciferase complementation. This technique enables protein-protein interactions to co-education argument, be detected intracellularly in living cells. This technique has a wide variety of possible applications, such as phosphorylation monitoring, G-protein-coupled receptor screening, and even Ph monitoring in addition to observing protein-protein interactions. Dragulescu-Andrasi et. Cover Letter For Creative Position. al. further emphasize the co-education importance of being able to identify and understand various interactions between proteins in the cell. They describe a system using bioluminescence resonance energy transfer that makes it possible to identify protein-protein interactions not only in culture, but in animals deep tissue in a living organism. They outline the potential usages of this system to investigate protein-protein interactions in essay the context of target validation and drug screening in a patient.

The potential usage of this technique is wonderful, especially because of on man's its non-invasive requirements. Wehrman et. Argument. al., generated a sequential reporter enzyme that works to report beta-galactosidase activity in vivo using luminescence. This was accomplished using a caged D-luciferin-galactoside conjugate which must react with beta-galactosidase before the luciferin can be released to create luminescence. They state that one benefit of this method, besides the non-invasiveness that comes with using bioluminescence, is the ability for the probe to remain fully active even when it is outside of the cell since beta-galactosidase is able function without the letter for creative position aid of co-education essay intracellular enzymes. Because of this ability, antibodies conjugated to the recombinant beta-galactosidase can be used to television shows, detect extracellular antigens or other endogenous cells in co-education vivo, which provides applications that weren’t previously possible with older methods. In an experiment conducted by persuasive Hickson et. al., a useful method using bioluminescence has the potential to deliver rapid and sensitive feedback regarding drug efficacy and therapeutic action. Using a modified version of luciferin called Z-DEVD-aminoluciferin, they measured the amount of luminescence delivered after injecting this modified luciferin into cancerous animals prior to treatment with docetaxel.

They also had a control group who were not injected with docetaxel. Z-DEVD-aminoluciferin is cleaved by co-education argument essay caspase-3, which is released in study on diabetes apoptotic cells, which in turn releases the luciferin and results in co-education luminescence. Vs Contrast. Light was detected in significantly greater amounts in co-education essay the group that was treated with docetaxel. What was even more significant to letter position, note was that these significant readings which occurred at approximately 24 hours after treatment confirmed what a caliper measurement showed nearly 4-5 days later. This helps to illustrate the possibility bioluminescence has in terms of testing drug functionality in vivo. Knowledge of how a drug is working can be obtained many days before older methods could measure. Van de Bittner et. al. conducted an experiment using bioluminescence and related it to argument essay, hydrogen peroxide.

It is study insipidus known that hydrogen peroxide is generated by living organisms to kill invading pathogens and to maintain immunity. The specifics on co-education essay, hydrogen peroxide’s general effects on aging and health are largely unknown largely attributed to on man's, the difficulties of co-education essay being able to study it in vivo. In their experiment they report on compare essay, their use Peroxy Caged Luciferin-1 which serves as a bioluminescent probe that selectively reacts with hydrogen peroxide, causes the release of luciferin and consequently creates luminescence. Because of the sensitivity and co-education argument, selectivity of Peroxy Caged Luciferin-1, a real time image of basal levels of hydrogen peroxide can be observed. The effects of hydrogen peroxide, in addition to argumentative television, all kinds of co-education argument essay other chemicals, on aging, disease and argumentative essays on reality shows, health can now be observed where previously it was impossible.

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